Tag Archives: apoptosis

Monsanto Corn Causes Liver and Kidney Damage in Rats

The researchers used Monsanto’s own data, which was for a period of ingestion of only 90 days, and reached these conclusions:
We therefore conclude that our data strongly suggests that these GM maize varieties induce a state of hepatorenal [liver and kidney] toxicity. This can be due to the new pesticides (herbicide or insecticide) present specifically in each type of GM maize, although unintended metabolic effects due to the mutagenic properties of the GM transformation process cannot be excluded [42]. All three GM maize varieties contain a distinctly different pesticide residue associated with their particular GM event (glyphosate and AMPA in NK 603, modified Cry1Ab in MON 810, modified Cry3Bb1 in MON 863).
Why should GM foods have this sort of effect?
These substances have never before been an integral part of the human or animal diet and therefore their health consequences for those who consume them, especially over long time periods are currently unknown.
Humans generally have centuries of experience with most other foods, and have rejected or developed appropriate preparation methods for those that are toxic.

Plus until recently humans weren’t in the habit of eating pesticides that had been deliberately engineered to be toxic to other species. Especially without testing first to see if they might be toxic to humans….

One of the four authors of this research paper in the peer-reviewed International Journal of Biological Sciences, Gilles-Eric Seralini, had already established that Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells. In other words, RoundUp causes human birth defects. So if Monsanto’s pesticide doesn’t get you or your children directly, it can still get you in your food. And maybe not just in food containing corn, given that chickens fed feed including Monsanto corn show abnormal gene expression. Maybe somebody will study people who eat chickens fed Monsanto corn and see what effects that has.

But remember, while the evidence mounts that Monsanto is poisoning the world’s food supply, Forbes just named Monsanto company of the year! All this other stuff is just economic externalities, and profit is all that matters!

Glysophate Effects on Humans: International Studies

Dr. Carrasco of Argentina isn’t alone, not worldwide. As Negin P. Martin, PH.D noted in June in Environmental Health News, studies in other countries show direct effects on humans:
For example, French scientists, Drs. Seralini and Benacour, have published a number of scientific papers about the harmful effects of Roundup and its ingredients on human embryonic and placental cells. A Swedish scientific team lead by Dr. Akerman published an epidemiological study disclosing that exposure to glyphosate is a risk factor for developing Non-Hodgkin lymphoma. Dr. Busbee – an American scientist – demonstrated alterations in estrogen-regulated genes after exposure to dilute concentrations of glyphosate.
Nora Benachour and Gilles-Eric Sralini report in Chem. Res. Toxicol., 2009, 22 (1), pp 97–105 about Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells:
We have evaluated the toxicity of four glyphosate (G)-based herbicides in Roundup (R) formulations, from 105 times dilutions, on three different human cell types. This dilution level is far below agricultural recommendations and corresponds to low levels of residues in food or feed. The formulations have been compared to G alone and with its main metabolite AMPA or with one known adjuvant of R formulations, POEA. HUVEC primary neonate umbilical cord vein cells have been tested with 293 embryonic kidney and JEG3 placental cell lines. All R formulations cause total cell death within 24 h, through an inhibition of the mitochondrial succinate dehydrogenase activity, and necrosis, by release of cytosolic adenylate kinase measuring membrane damage.
And it gets even better:
The deleterious effects are not proportional to G concentrations but rather depend on the nature of the adjuvants. AMPA and POEA separately and synergistically damage cell membranes like R but at different concentrations. Their mixtures are generally even more harmful with G. In conclusion, the R adjuvants like POEA change human cell permeability and amplify toxicity induced already by G, through apoptosis and necrosis. The real threshold of G toxicity must take into account the presence of adjuvants but also G metabolism and time-amplified effects or bioaccumulation.
Glysophate makes other chemicals even more toxic, and remember Glysophate doesn’t break down rapidly and tends to accumulate in organisms. Organisms such as you and your children.